TYPES OF PNEUMOCOCCAL VACCINES
Vaccination against a pneumococcal bacterial infection helps prevent you or your child from becoming sick from pneumococcal diseases. It also aids in preventing these diseases from spreading within your community. So, today we are going to discuss about each and every type of pneumonia vaccine available in India.
Vaccination can’t always prevent all cases of pneumococcal disease. Nevertheless, according to the Centers for Disease Control and Prevention (CDC), even just one doseTrusted Source can help protect against a variety of pneumococcal infections.
Mainly there are 2 types of vaccine: Conjugate & Polysaccharide vaccine
CONJUGATE VACCINES ARE:
PCV13: PREVENAR 13 (by PFIZER)
PCV10: SYNFLORIX (by GSK)
PCV10: PNEUMOSIL (by SERUM INSTITUTE)
POLYSACCHARIDE VACCINE IS:
PNEUMOVAX23 (by MSD)
WHAT TO PREFER CONJUGATE VACCINES OR POLYSACCHARIDE VACCINES?
Conjugate vaccines are preferred over Polysaccharide vaccines because:
- antibody response is generated within 2-4 weeks of immunisation after polysaccharide vaccine but it generates predominantly Ig M response with low titres of low affinity Ig G. Thus the half-life of plasma cells is short and antibody titres decline rapidly.
- polysaccharide vaccine are unable to evoke an immune response in those aged less than 2 years due to immaturity of the marginal zones
- as polysaccharide vaccine do not induce germinal centres bonafide, memory B cells are not elicited. Thus repeat exposure of same polysaccharide antigen results in a primary response that follows the same kinetics in previously vaccinated as in naïve individuals.
So it is better to vaccinate your child with conjugate vaccines as they give a life-long immunity to the individual.
Let us know about each of the vaccine in details!!
What are the serotypes that are covered? What is the brand name? Produced by which company? For whom it is recommended? Vaccination schedule? and most importantly price of the vaccine…
PCV13 (pneumococcal conjugate vaccine) PREVANAR 13
This vaccine provides protection against 13 strains of pneumococcal bacteria that commonly cause disease in children and adults. It’s given as 3+1 doses in children and one dose in adults.
13 serotypes that are covered: 4, 6B, 9V, 14, 18C, 19F, 23F, 1, 5, 7F, 3, 6A, 19A
PCV13 is recommended to:
- babies
- adults age 65 and older
- people aged 2 to 64 with certain health conditions, such as diabetes mellitus, HIV, or chronic conditions of the heart, kidneys, liver, or lungs
Prevenar 13 (PCV 13) price in India
MRP 3800/- (Doctor may charge from 4000 to 4500/- based on their knowledge, experience and availability)
PCV10 (pneumococcal conjugate vaccine) SYNFLORIX
This vaccine provides protection against 10 strains of pneumococcal bacteria that commonly cause disease in children and adults. It’s given as 3+1 doses in children.
Serotypes that are covered: 4, 6B, 9V, 14, 18C, 19F, 23F, 1, 5, 7F.
Not present serotypes are 3, 6A & 19A.
PCV10 is recommended to: